Module CS4440-KP04, CS4440

Molecular Bioinformatics (MolBioInfo)


Duration

1 Semester

Turnus of offer

each winter semester

Credit points

4

Course of studies, specific fields and terms:

  • Master CLS 2023, optional subject, computer science
  • Master Molecular Life Science 2023, optional subject, mathematics / computer science
  • Master CLS 2016, optional subject, computer science
  • Master MES 2011, advanced curriculum, biophysics and biomedical optics
  • Master CLS 2010, optional subject, computer science
  • Master Computer Science 2012, compulsory, specialization field bioinformatics

Classes and lectures:

  • Molecular Bioinformatics (exercise, 1 SWS)
  • Molecular Bioinformatics (lecture, 2 SWS)

Workload:

  • 45 hours in-classroom work
  • 55 hours private studies
  • 20 hours exam preparation

Contents of teaching:

  • Methods for fast genome comparison
  • Analysis of data describing gene expression profiles and sequence variation
  • Advanced usage of biological databases (for sequences, motifs, structures, gene regulation and interactions)

Qualification-goals/Competencies:

  • The students can apply indexing based software to Next Generation sequence data.
  • They can use and design databases for molecularbiological research.
  • They are able to detect statistically significant changes in Microarray data.

Grading through:

  • written exam

Responsible for this module:

Literature:

  • M. S. Waterman : Introduction to Computational Biology London: Chapman and Hall 1995
  • B. Haubold, T. Wiehe : Introduction to Computational Biology Birkhäuser 2007
  • R. Durbin, S. Eddy, A. Krogh, G. Mitchison : Biological sequence analysis. Probabilistic models Cambridge, MA: Cambridge University Press
  • J. Setubal, J. Meidanis : Introduction to computational molecular Pacific Grove: PWS Publishing Company
  • D. M. Mount : Bioinformatics - Sequence and Genome New York: Cold Spring Harbor Press

Language:

  • English, except in case of only German-speaking participants

Notes:

Prerequisites for the module:
- None

Prerequisites for admission to the written examination:
- Successful completion of exercises as specified at the beginning of the semester

Module exam(s):
- CS4440-L1: Molecular Bioinformatics, written exam, 90 min, 100 % of module grade

Last Updated:

05.09.2022