Module MA3200-KP04, MA3200
Genetic Epidemiology 1 (GenEpi1)
Duration
1 Semester
Turnus of offer
each winter semester
Credit points
4
Course of studies, specific fields and terms:
- Bachelor CLS 2023, compulsory, mathematics
- Master Medical Informatics 2019, optional subject, Medical Data Science / Artificial Intelligence
- Bachelor CLS 2016, compulsory, mathematics
- Master Medical Informatics 2014, optional subject, ehealth / infomatics
- Master Computer Science 2012, optional subject, specialization field medical informatics
- Bachelor CLS 2010, compulsory, mathematics
Classes and lectures:
- Genetic Epidemiology 1 (exercise, 1 SWS)
- Genetic Epidemiology 1 (lecture, 2 SWS)
Workload:
- 45 hours in-classroom work
- 15 hours exam preparation
- 60 hours private studies
Contents of teaching:
- Monogenic and complex diseases
- Hardy-Weinberg-equilibrium
- Coupling imbalance
- Genetic markers and genotyping
- Quality control
- Basics of association analysis
- Genome-wide association studies
- Population stratification
- Gene-environment interaction
- Replication, meta-analysis and imputation
- Ethical aspects
Qualification-goals/Competencies:
- Students are able to describe the generation of genetic data, its error sources and methods of detection.
- They can select and describe the most important approaches for genetic epidemiological association studies on the level of single markers.
- They are able to apply the basic test procedures manually and to interpret the results.
- They are able to describe the statistical evaluation steps in a genome-wide association study and interpret the results.
Grading through:
- Written or oral exam as announced by the examiner
Responsible for this module:
- Prof. Dr. rer. nat. Silke Szymczak
Teacher:
- Institute of Medical Biometry and Statistics
- Prof. Dr. rer. nat. Silke Szymczak
- MitarbeiterInnen des Instituts
Literature:
- Ziegler A, König IR. : A statistical approach to genetic epidemiology. Concepts and applications. 2010. ISBN: 978-3-527-32389-0
- Bickeböller H, Fischer, C : Einführung in die Genetische Epidemiologie 2007. ISBN: 978-3-540-25616-8
Language:
- German or English
Notes:
Prerequisites for attending the module:- None (The competencies of the modules listed under 'Requires' are needed for this module, but are not a formal prerequisite)
Prerequisites for the exam:
- Examination prerequisites can be defined at the beginning of the semester. If preliminary work is defined, it must have been completed and positively evaluated before the first examination.
Module exam(s):
- MA3200-L1: Genetic Epidemiology 1, oral exam, 30 min, or written exam, 90 min, 100% of module grade
Last Updated:
12.09.2024