Module LS4030-KP06

Molecular Pathomechanisms and Strategies for Therapy (Pathom)


Duration

1 Semester

Turnus of offer

each winter semester

Credit points

6

Course of studies, specific fields and terms:

  • Master Molecular Life Science 2023, compulsory, life sciences
  • Master MLS 2018, compulsory, cell biology
  • Master MLS 2016, compulsory, cell biology
  • Master MLS 2009, compulsory, life sciences

Classes and lectures:

  • Molecular Pathomechanisms and Strategies for Therapy (lecture, 4 SWS)

Workload:

  • 120 hours private studies
  • 60 hours in-classroom work

Contents of teaching:

  • Mechanisms of tumor initiation and tumor progression
  • Oncogenes und tumor suppressor genes
  • Correlation of DNA damage and tumorigenesis
  • Tumor-inducing pathogens
  • Metastasis and angiogenesis
  • pathways, regulation and pathological relevant deregulation of apoptosis
  • microRNAs: a new player in cancer development
  • Tumor diagnostic
  • Therapeutic concepts

Qualification-goals/Competencies:

  • The attendants of the course are able to describe the various general mechanisms of tumor initiation and tumor progression and discuss the terms and definitions in the overall context of tumor biology as well as apply them to given examples
  • The students are qualified to explain correlations between tumor biology and pathogenic mechanisms in apoptosis, RNA interference and tumor-inducing viruses and bacteria.
  • Furthermore, they can assess which concepts for tumor diagnosis and therapy are reasonably applied in the clinic and can evaluate to what extent alternative therapeutic concepts can be used in the correlation to their current limitations.

Grading through:

  • written exam

Responsible for this module:

  • Prof. Dr. rer. nat. Timo Gemoll, MSc

Teacher:

  • University of Luebeck
  • Prof. Dr. rer. nat. Timo Gemoll, MSc
  • N.N.

Literature:

  • V. DeVita, S. Rosenberg and T. Lawrence : DeVita, Hellman, and Rosenberg’s – Cancer – Principles & Practice of Oncology, Lippincott Williams & Wilki; Auflage 5 oder höher; ISBN: 978-0397515745
  • G. Löffler et al. : Biochemie und Pathobiochemie Berlin, 11/2006, ISBN 978-3540326809
  • C. Wagener & O. Müller : Molekulare Onkologie: Entstehung, Progression, klinische Aspekte Stuttgart, 10/2009, ISBN-13: 978-3131035134
  • R. A. Weinberg : The Biology of Cancer Garland Publishing Inc, 7/2006, ISBN-13: 978-0815340782
  • : Current research and review articles

Language:

  • English, except in case of only German-speaking participants

Notes:

Prerequisites for the module:
- BSc in Molecular Life Science or related fields

Prerequisites for admission to the written examination:
- nothing

Module exam:
- LS4030-L1: Moleculare Pathomechanisms and Therapeutic Strategies, written exam, 90 min, 100 % module grade

Last Updated:

29.09.2022