Module MA4100-KP05

Survival Analysis (UebAnaKP05)


Duration

1 Semester

Turnus of offer

irregularly

Credit points

5

Course of studies, specific fields and terms:

  • Master CLS 2023, optional subject, mathematics
  • Bachelor CLS 2023, optional subject, mathematics
  • Bachelor CLS 2016, optional suject, mathematics
  • Master CLS 2016, optional subject, mathematics

Classes and lectures:

  • Survival Analysis (exercise, 1 SWS)
  • Survival Analysis (lecture, 2 SWS)

Workload:

  • 30 hours work on project
  • 15 hours in-classroom work
  • 90 hours private studies
  • 15 hours exam preparation

Contents of teaching:

  • Introduction to survival analysis
  • Kaplan-Meier method
  • Log rank test
  • The Cox regression model and its characteristics
  • Evaluating the proportional hazards assumption
  • Stratified Cox model
  • Parametric survival analysis
  • Event time analyses for recurrent events
  • Event time analysis for competing risks
  • Design aspects for RCTs

Qualification-goals/Competencies:

  • The students are able to explain the different censoring mechanisms leading to survival analysis.
  • They are able to define the most important terms of survival analysis.
  • They are able to calculate point and interval estimators for the Kaplan- Meier approach.
  • They are able to calculate the log-rank test for two or more groups.
  • They are able to explain the assumption of proportionality of the Cox model.
  • They are able to estimate Cox models.
  • They are able to check the assumption of proportionality.
  • They are able to calculate exponential and Weibull models.
  • They can explain the specifics of recurrent events and competing risks.
  • They can estimate models for recurrent events and competing risks.
  • They can design an RCT with a time-to-event endpoint.

Grading through:

  • Oral examination

Responsible for this module:

  • Dr. Maren Vens

Literature:

  • Kleinbaum DG, Klein M : Survival Analysis: A Self-Learning Text - 3rd Edition - 2012

Language:

  • English, except in case of only German-speaking participants

Notes:

Admission requirements for taking the module:
- None (The competencies of the modules listed under 'Requires' are needed for this module, but are not a formal prerequisite)

Admission requirements for participation in module examination(s):
- Successful completion of homework assignments as specified at the beginning of the semester

Module exam(s):
- MA4100-L1: Survival Analysis, oral exam, 30 min, 100 % of module grade

Last Updated:

22.02.2022