Module LS4145-KP05

Duration

1 Semester

Turnus of offer

each summer semester

Credit points

5

Course of studies, specific fields and terms:

• Master Infection Biology 2023, compulsory, Infection Biology
• Master Infection Biology 2018, compulsory, Infection Biology
• Master Infection Biology 2012, compulsory, Infection Biology

Classes and lectures:

• Infection Biology 2 (practical course, 3 SWS)
• Infection Biology 2 (lecture, 2 SWS)

Workload:

• 75 hours in-classroom work
• 75 hours private studies

Contents of teaching:

• Cellular and molecular mechanisms of infections
• Interaction of pathogens with cells of the innate and adaptive immune system, antimicrobial effector mechanisms
• Extra- and intracellular pathogens, molecular mechanisms of intracellular survival
• Host cell death and its consequences
• Innate and adaptive immune functions and practical applications
• Background and practical application of cell culture, virus cultivation, and virus quantification (Endpoint titration and plaque assay)
• Aseptic techniques
• Basic knowledge in genetic engineering and legislation, in Good Scientific Practis with regards to teh rules of the UzL.
• Laboratory safety (GHS)
• Basic laboratory calculations

Qualification-goals/Competencies:

• The students have the scientific competency to implement their detailed knowledge of infectious agents, infectious diseases and their pathomechanisms, their detailed understanding of antimicrobial defense mechanisms at the cellular and molecular level.
• They are competent in theory and in practical skills in laboratory techniques to approach infectious disease research projects in a successful manner with regards to teh rules of Good Scientific Practise of the UzL.
• They know the principles of virus cultivation and titration and can apply this practically.
• They know the principles of tissue culture and can apply this practically.
• They can perform standard laboratory calculations and unit conversions.
• They have the methodological competence, to use flow cytometric approaches addressing the host-pathogen interaction at single cell level (phagocytosis, cell activation, cell death, cytokine formation).
• They can process and interpret data and can communicate it to peers
• They have the communication competency to convey the underlying principles of techniques of infection research.
• They understand laboratory safety procedures and can apply them practically

Grading through:

• Oral examination

Is requisite for:

• Internship (LS4115-KP16)

Requires:

• Diagnostical Methods in Microbiology and Pathology (LS4045-KP05)
• Infection Biology 1 (LS4015-KP06)

Responsible for this module:

• Prof. Dr. rer. nat. Stefan Taube

Teacher:

• Department of Infectiology
• Institute for Systemic Inflammation Research (ISEF)
• Institute of Virology and Cell Biology
• Research Center Borstel, Leibniz Lung Center
• Institute of Medical Microbiology
• Prof. Dr. Ulrich Schaible
• Prof. Ph.D. Tamás Laskay
• Prof. Dr. rer. nat. Christian Karsten
• PD Dr. rer. nat. Norbert Reiling
• Prof. Dr. rer. nat. Stefan Taube
• Dr. math. et dis. nat. Jeroen Mesters
• Dr. rer. nat. Tobias Dallenga

Literature:

• S.J. Flint : Principles of Virology – Vol I and II ASM Press, Washington DC
• • Mims' Pathogenesis of Infectious Disease. : Academic Press. Ed. Nash, Dalziel, Fitzgerald
• Carter, J., & Saunders, V. A. : Virology: principles and applications. 2007 John Wiley & Sons.

Language:

• offered only in English

Notes:

Last Updated:

28.11.2024